Gregory B Vanden Heuvel, PhD

Gregory B Vanden Heuvel, PhD
Gregory B Vanden Heuvel, PhD

Associate Dean for Foundational Research

Associate Dean for Research

Professor, Department of Biomedical Sciences

Contact Information

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Biosketch

Gregory Vanden Heuvel, PhD, is a professor in the Department of Biomedical Sciences of 汤头条app in Kalamazoo, Michigan.

Dr. Vanden Heuvel is a graduate of Grand Valley State University in Allendale, Michigan. He earned a master's degree in biological sciences from Western Michigan University in Kalamazoo, Michigan. He earned his doctorate in cell biology from University of Alabama at Birmingham in Birmingham, Alabama. He also completed a fellowship in developmental nephrology at Yale University School of Medicine.

Dr. Vanden Heuvel has extensive experience in teaching and developing curricula and education materials for medical students. He has research interests in the area of transcriptional regulation of kidney development.

  • 汤头条app and Training
    • Fellowship 1997, Developmental Nephrology, School of Medicine, Yale University
    • PhD 1994, Cell Biology, University of Alabama at Birmingham
    • MS 1988, Biomedical Sciences, Western Michigan University
    • BS 1984, Biology, Grand Valley State University

  • Research
    • Renal Development
    • Polycystic Kidney Diseases
    • Molecular Biology
    • Developmental Biology
    • Cell Biology

  • Publications

    • Griesmann H., M眉hl S., Riedel J., Theuerkorn K., Sipos B., Esposito I., Heuvel G.B.V., Michl P. Cux1 enhances pancreatic cancer formation by synergizing with kras and inducing mek/erk鈥恉ependent proliferation Cancers. 2021;13(10)

    • Srivastava T., Joshi T., Heruth D.P., Rezaiekhaligh M.H., Garola R.E., Zhou J., Boinpelly V.C., Ali M.F., Alon U.S., Sharma M., Vanden Heuvel G.B., Mahajan P., Priya L., Jiang Y., McCarthy E.T., Savin V.J., Sharma R. Scientific Reports. 2021;11

    • Livingston S., Carlton C., Sharma M., Kearns D., Baybutt R., Vanden Heuvel G.B. Gene: X. 2019;2

    • Puri R.V., Yerrathota S., Home T., Idowu J.Y., Chakravarthi V.P., Ward C.J., Singhal P.C., Heuvel G.B.V., Fields T.A., Sharma M. DMM Disease Models and Mechanisms. 2019;12

    • Porath B., Livingston S., Andres E.L., Petrie A.M., Wright J.C., Woo A.E., Carlton C.G., Baybutt R., Vanden Heuvel G.B. American Journal of Physiology - Renal Physiology. 2017;313(4):F1050-F1059.

    • Keator C., Dickinson B.L., Lackey W.L., Morris A., Quesnelle K.M., Riddle D.R., Sheakley M.L., Vanden Heuvel G.B., Vandre D.D. Explorations: a New Approach to Self-Directed Learning in a Competency-Based Curriculum Medical Science Educator. 2016;26:777-785.

    • Paul B., Vanden Heuvel G. Wiley Interdisciplinary Reviews: Developmental Biology. 2014;3(6):465-487.

    • Sharma M., Magenheimer L.K., Home T., Tamano K.N., Singhal P.C., Hyink D.P., Klotman P.E., Vanden Heuvel G.B., Fields T.A. American Journal of Physiology - Renal Physiology. 2013;304(8):1127-1136.

    • Sharma N., Malarkey E.B., Berbari N.F., O'Connor A.K., Heuvel G.B.V., Mrug M., Yoder B.K. Journal of the American Society of Nephrology. 2013;24(3):456-464.

    • Kroll M., Viss E.S., Lamb J., Horstman J., Powell A., Van Wyk A., Hinkkala K., Hoogland T., Schippers M., Shannon S., Carlton C.G., Sharma M., Taylor A., Vanden Heuvel G.B., Jelsma T.N. Biology of Reproduction. 2011;84(3):455-465.

    • Paul B.M., Vassmer D., Taylor A., Magenheimer L., Carlton C.G., Piontek K.B., Germino G.G., Vanden Heuvel G.B. Developmental Dynamics. 2011;240(6):1493-1501.

    • Sharma M., Callen S., Zhang D., Singhal P.C., Vanden Heuvel G.B., Buch S. AIDS. 2010;24(14):2161-2170.

    • Vanden Heuvel G.B. Kidney International. 2010;78(6):537-538.

    • Alcalay N.I., Vanden Heuvel G.B. Frontiers in Bioscience. 2009;14(13):4978-4991.

    • Iulianella A., Sharma M., Vanden Hauvel G.B., Trainor P.A. Development. 2009;136(14):2329-2334.

    • Sharma M., Brantley J.G., Vassmer D., Chaturvedi G., Baas J., Vanden Heuvel G.B. Gene. 2009;439(1-2):87-94.

    • Alcalay N.I., Sharma M., Vassmer D., Chapman B., Paul B., Zhou J., Brantley J.G., Wallace D.P., Maser R.L., Vanden Heuvel G.B. American Journal of Physiology - Renal Physiology. 2008;295(6)

    • Iulianella A., Sharma M., Durnin M., Vanden Heuvel G.B., Trainor P.A. Development. 2008;135(4):729-741.

    • Alcalay N.I., Brantley J.G., Sharma M., Gooch J.L., Vanden Heuvel G.B. Developmental Dynamics. 2007;236(1):184-191.

    • Vanden Heuvel G.B., Payne J.A., Igarashi P., Forbush B. Gene Expression Patterns. 2006;6(8):1000-1006.

    • Sharma M., Brantley J.G., Alcalay N.I., Zhou J., Heystek E., Maser R.L., Vanden Heuvel G.B. Kidney International. 2005;67(2):432-442.

    • Vanden Heuvel G.B., Brantley J.G., Alcalay N.I., Sharma M., Kemeny G., Warolin J., Ledford A., Pinson D.M. Molecular Carcinogenesis. 2005;43(1):18-30.

    • Sharma M., Fopma A., Brantley J.G., Vanden Heuvel G.B. Developmental Dynamics. 2004;231(4):828-838.

    • Brantley J.G., Sharma M., Alcalay N.I., Vanden Heuvel G.B. Kidney International. 2003;63(4):1240-1248.

    • Goyal S., Vanden Heuyel G., Aronson P.S. American Journal of Physiology - Renal Physiology. 2003;284(3 53-3)

    • Iulianella A., Vanden Heuvel G., Trainor P. Gene Expression Patterns. 2003;3(5):571-577.

    • Ledford A., Brantley J.G., Kemeny G., Foreman T., Quaggin S.E., Igarashi P., Oberhaus S.M., Rodova M., Calvet J.P., Vanden Heuvel G.B. Developmental Biology. 2002;245(1):157-171.

    • Quaggin S., Vanden Heuvel G., Igarashi P. Mechanisms of Development. 1998;71(1-2):37-48.

    • Taylor H.S., Vanden Heuvel G.B., Igarashi P. Biology of Reproduction. 1997;57(6):1338-1345.

    • Quaggin S.E., Vanden Heuvel G.B., Golden K., Bodmer R., Igarashi P. Journal of Biological Chemistry. 1996;271(37):22624-22634.

    • Vanden Heuvel G.B., Bodmer R., Mcconnell K.R., Nagami G.T., Igarashi P. Kidney International. 1996;50(2):453-461.

    • Vanden Heuvel G.B., Leardkamolkarn V., St. John P.L., Abrahamson D.R. Kidney International. 1996;49(3):752-760.

    • Vanden Heuvel G.B., Quaggin S.E., Igarashi P. Biology of Reproduction. 1996;55(4):731-739.

    • Igarashi P., Vanden Heuvel G.B., Payne J.A., Forbush B. American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 1995;269(3 38-3)

    • Vanden Heuvel G.B., Abrahamson D.R. American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 1993;265(2 34-2)

  • Presentations
    • Molecular model for two hit somatic mutations in autosomal dominant polycystic kidney disease. Kooistra J, Parsons A, Bungha Tita LV, Bouma G, Vanden Heuvel G, Larson E, 42nd Annual Kalamazoo Community and Health Sciences Research Day, Kalamazoo, Michigan, 04/2024
    • The impact of G-quadruplex DNA on expression of the human PKD1 gene. Byrne S, Parsons A, Bouma G, Vanden Heuvel G, Larson E, 42nd Annual Kalamazoo Community and Health Sciences Research Day, Kalamazoo, Michigan, 04/2024
    • Visualization of DNA G-Quadruplex Structures and PKD1 in Human Kidney Cells and Polycystic Kidney Disease. Kooistra J, Su K, Byrne S, Lopez A, Vanden Heuvel G, Larson E, Bouma G, 41st Annual Kalamazoo Community Medical & Health Sciences Research Day, Kalamazoo, Michigan, 05/2023
    • The Cux1 and Polycystin1 proteins are regulated by the Notch signaling pathway in the developing kidney. Vanden Heuvel G, Su K, 40th Annual Kalamazoo Community Medical and Health Sciences Research Day, Kalamazoo, Michigan, 04/2022
    • A Role for Cut homeobox 1 in Scoliosis Pathogenesis and Spine Deformity. Beck E, Vanden Heuvel G, Akkouch A, 40th Annual Kalamazoo Community Medical and Health Sciences Research Day, Kalamazoo, Michigan, 04/2022
    • Deletion of the Homeobox Gene CUX1 Decreases Ciliogenesis in a Mouse Model of Polycystic Kidney Disease. Holthaus C, Rumschlag M, Kumar E, Wee ZN, Pasillas M, Vanden Heuvel G, 38th Annual Kalamazoo Community Medical and Health Sciences Virtual Research Day, Kalamazoo, Michigan, 04/2021
    • Overexpression of the Homeobox Gene CUX1 in Transgenic Mice Increases Ciliogenesis in the Kidney. Kumar E, Rumschlag M, Holthaus C, Wee ZN, Pasillas M, Vanden Heuvel G, 38th Annual Kalamazoo Community Medical and Health Sciences Virtual Research Day, Kalamazoo, Michigan, 04/2021